Virtual Special Issue: Conference on Physiology of Yeasts and Filamentous Fungi (PYFF6)

The synergistic convergence of powerful experimental strategies, in particular the genome-based approaches, are unveiling fascinating aspects of the physiology of yeasts and filamentous fungi, boosting the understanding of these eukaryotic microorganisms and their exploitation in biotechnology and for the bioremediation of recalcitrant organic pollutants or the control of their unwanted or pathogenic activities. These studies are also instrumental to understand the economic and environmental benefits of biodiversity, the evolutionary effects of domestication, the deleterious action of environmental pollutants that pose potential risk to human health. The exploitation of advanced genome redesign and evolution and of physiological genomics and metabolic engineering and synthetic biology approaches to enable the generation of novel cell factories that efficiently convert renewable feedstocks into biofuels, bulk, and fine chemicals, thus creating the basis for biosustainable economy, is gaining increased attention.

Top-level research on Physiology of Yeasts and Filamentous Fungi is published in two FEMS journals, FEMS Yeast Research and FEMS Microbiology Letters, and some of the best representative papers from the two journals were collected in this joint virtual issue. We hope you will enjoy reading these exciting papers and consider submitting your discoveries on the Physiology of Yeasts and Filamentous Fungi to these journals in the near future.

Read the conference report here.

Articles selected by Isabel Sá-Correia.

Widespread ability of fungi to drive quinone redox cycling for biodegradation
Martin C. Krueger, Michael Bergmann, Dietmar Schlosser
FEMS Microbiology Letters (2016) 363 (11) DOI:

Complete genome sequence and transcriptome regulation of the pentose utilizing yeast Sugiyamaella lignohabitans
Martina Bellasio, Armin Peymann, Matthias G. Steiger, Minoska Valli, Matthias Sipiczki, Michael Sauer, Alexandra B. Graf, Hans Marx, Diethard Mattanovich FEMS Yeast Research (2016) 16 (4) DOI:

n-butanol: challenges and solutions for shifting natural metabolic pathways into a viable microbial production
Paola Branduardi, Danilo Porro
FEMS Microbiology Letters (2016) 363 (8) DOI:

Replacement of the initial steps of ethanol metabolism in Saccharomyces cerevisiae by ATP-independent acetylating acetaldehyde dehydrogenase
Barbara U. Kozak, Harmen M. van Rossum, Matthijs S. Niemeijer, Marlous van Dijk, Kirsten Benjamin, Liang Wu, Jean-Marc G. Daran, Jack T. Pronk, Antonius J.A. van Maris
FEMS Yeast Research (2016) 16 (2) DOI:

Cadmium-induced cell killing in Sacharomyces cerevisiae involves increases in intracellular NO levels
Lihua Wu, Yanfei Chen, Huixian Gao, Jingjing Yin, Liqun Huang
FEMS Microbiology Letters (2016) 363 (6) DOI:

Improved production of fatty acids by Saccharomyces cerevisiae through screening a cDNA library from the oleaginous yeast Yarrowia lipolytica
Shuobo Shi, Haichuan Ji, Verena Siewers, Jens Nielsen
FEMS Yeast Research (2015) 16 (1): DOI:

Isolation and identification of nematode-antagonistic compounds from the fungus Aspergillus candidus
Olga N. Shemshura, Nadiya E. Bekmakhanova, Mariya N. Mazunina, Susan L. F. Meyer, Clifford P. Rice, Edward P. Masler
FEMS Microbiology Letters (2016) 363 (5) DOI: fnw026

Diversity and adaptive evolution of Saccharomyces wine yeast: a review
Souhir Marsit, Sylvie Dequin
FEMS Yeast Research (2015) 15 (7) DOI:

Fungal denitrification: Bipolaris sorokiniana exclusively denitrifies inorganic nitrogen in the presence and absence of oxygen
Rebecca Phillips, Gwen Grelet, Andrew McMillan, Bongkeun Song, Bevan Weir, Thilak Palmada, Craig Tobias
FEMS Microbiology Letters (2016) 363 (4) DOI:

Tipping the balance both ways: drug resistance and virulence in Candida glabrata  
Luis A. Vale-Silva, Dominique Sanglard  
FEMS Yeast Research (2015) 15 (4) DOI:

Drosophila-associated yeast species in vineyard ecosystems
Samuel S. T. H. Lam, Kate S. Howell
FEMS Microbiology Letters (2016) 362 (20) DOI:

Application of synthetic biology for production of chemicals in yeast Saccharomyces cerevisiae
Mingji Li, Irina Borodina
FEMS Yeast Research (2015) 15 (1) DOI: